PRPF8 - MED12

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PRPF8	ENSG00000174231	No diseases in record	No drugs in record	second spliceosomal transesterification activity protein binding U6 snRNA binding U1 snRNA binding U2 snRNA binding U5 snRNA binding K63-linked polyubiquitin binding pre-mRNA intronic binding	PRP8 (S. cerevisiae)
MED12	ENSG00000184634	uterine leiomyoma fibroadenoma phyllodes tumour	No drugs in record	RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription cofactor activity RNA polymerase II transcription coactivator activity chromatin binding transcription cofactor activity transcription coactivator activity receptor activity protein binding beta-catenin binding protein C-terminus binding protein domain specific binding ligand-dependent nuclear receptor transcription coactivator activity vitamin D receptor binding thyroid hormone receptor binding ubiquitin protein ligase activity	dpy-22 (C. elegans) kto (D. melanogaster)