PTPN11 - IRS2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PTPN11	ENSG00000179295	JMML AML MDS	No drugs in record	phosphoprotein phosphatase activity protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity SH3/SH2 adaptor activity insulin receptor binding protein binding 1-phosphatidylinositol-3-kinase activity protein domain specific binding receptor tyrosine kinase binding D1 dopamine receptor binding phospholipase binding insulin receptor substrate binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity cell adhesion molecule binding peptide hormone receptor binding	PTP1 (S. cerevisiae) ptp-2 (C. elegans) csw (D. melanogaster)
IRS2	ENSG00000185950	No diseases in record	No drugs in record	signal transducer activity Ras guanyl-nucleotide exchange factor activity insulin receptor binding protein binding 1-phosphatidylinositol-3-kinase activity protein kinase binding protein phosphatase binding protein domain specific binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity 14-3-3 protein binding	chico (D. melanogaster)