TOP2B - RAD21

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
TOP2B ENSG00000077097

No diseases in record

ETOPOSIDE
TENIPOSIDE
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA binding, bending
enzyme binding
histone deacetylase binding
metal ion binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)
RAD21 ENSG00000164754 AML
endometrium
colorectal
lung

No drugs in record

transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
chromatin binding
protein binding
double-stranded DNA binding
scc-1 (C. elegans)
coh-1 (C. elegans)
vtd (D. melanogaster)