ERBB3 - MYC

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ERBB3 ENSG00000065361 colon
gastric
head and neck
bladder
skin
VANDETANIB
protein tyrosine kinase activity
transmembrane signaling receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
growth factor binding
protein tyrosine kinase activator activity
neuregulin binding
identical protein binding
protein homodimerization activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein heterodimerization activity
let-23 (C. elegans)
Egfr (D. melanogaster)
MYC ENSG00000136997 Burkitt lymphoma
amplified in other cancers
B-CLL

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
protein complex binding
protein dimerization activity
repressing transcription factor binding
E-box binding

No GO terms in record