PKN1 - HDAC2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PKN1	ENSG00000123143	No diseases in record	No drugs in record	chromatin binding protein kinase activity protein serine/threonine kinase activity protein kinase C activity protein kinase C binding protein binding ATP binding GTP-Rho binding ligand-dependent nuclear receptor transcription coactivator activity histone kinase activity (H3-T11 specific) histone binding histone deacetylase binding Rac GTPase binding androgen receptor binding	PKC1 (S. cerevisiae) pkn-1 (C. elegans) Pkn (D. melanogaster)
HDAC2	ENSG00000196591	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN VORINOSTAT	core promoter binding RNA polymerase II repressing transcription factor binding chromatin binding histone deacetylase activity protein binding transcription factor binding deacetylase activity enzyme binding heat shock protein binding NAD-dependent histone deacetylase activity (H3-K14 specific) protein deacetylase activity sequence-specific DNA binding NF-kappaB binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	RPD3 (S. cerevisiae) hda-1 (C. elegans) hda-3 (C. elegans)