ITCH - GLI1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ITCH	ENSG00000078747	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding ubiquitin-like protein transferase activity ribonucleoprotein complex binding CXCR chemokine receptor binding ubiquitin protein ligase activity	RSP5 (S. cerevisiae) wwp-1 (C. elegans) Su(dx) (D. melanogaster)
GLI1	ENSG00000111087	CRC oesophagus cancer	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding DNA binding chromatin binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding microtubule binding transcription regulatory region DNA binding metal ion binding	tra-1 (C. elegans)