UBE2I - HMGB1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
UBE2I	ENSG00000103275	No diseases in record	No drugs in record	protein binding ATP binding transcription factor binding ligase activity SUMO transferase activity enzyme binding HLH domain binding SUMO conjugating enzyme activity RING-like zinc finger domain binding ubiquitin protein ligase binding ubiquitin protein ligase activity	UBC9 (S. cerevisiae) lwr (D. melanogaster)
HMGB1	ENSG00000189403	No diseases in record	No drugs in record	four-way junction DNA binding bubble DNA binding lipopolysaccharide binding phosphatidylserine binding damaged DNA binding double-stranded DNA binding single-stranded DNA binding transcription factor activity, sequence-specific DNA binding double-stranded RNA binding single-stranded RNA binding cytokine activity protein binding transcription factor binding DNA binding, bending calcium-dependent protein kinase regulator activity lyase activity C-X-C chemokine binding protein kinase activator activity chemoattractant activity RAGE receptor binding DNA polymerase binding repressing transcription factor binding supercoiled DNA binding	NHP6A (S. cerevisiae) NHP6B (S. cerevisiae) hmg-1.2 (C. elegans)