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POLA1 - SKI
H. sapiens
SDL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
POLA1
ENSG00000101868
No diseases in record
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
NELARABINE
nucleotide binding
nucleoside binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
protein binding
3'-5' exonuclease activity
protein kinase binding
metal ion binding
protein heterodimerization activity
4 iron, 4 sulfur cluster binding
DNA primase activity
POL1 (S. cerevisiae)
DNApol-alpha180 (D. melanogaster)
SKI
ENSG00000157933
melanoma
No drugs in record
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription corepressor activity
protein binding
zinc ion binding
protein kinase binding
protein domain specific binding
ubiquitin protein ligase binding
SMAD binding
histone deacetylase inhibitor activity
repressing transcription factor binding
Snoo (D. melanogaster)