POLR2E - AGO2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLR2E	ENSG00000099817	No diseases in record	No drugs in record	DNA binding DNA-directed 5'-3' RNA polymerase activity protein binding RNA polymerase I activity RNA polymerase II activity RNA polymerase III activity	RPB5 (S. cerevisiae) rpb-5 (C. elegans) Rpb5 (D. melanogaster)
AGO2	ENSG00000123908	No diseases in record	No drugs in record	RNA 7-methylguanosine cap binding RNA polymerase II core binding core promoter binding double-stranded RNA binding single-stranded RNA binding mRNA binding translation initiation factor activity endoribonuclease activity protein binding protein C-terminus binding bidentate ribonuclease III activity siRNA binding miRNA binding metal ion binding endoribonuclease activity, cleaving siRNA-paired mRNA endoribonuclease activity, cleaving miRNA-paired mRNA mRNA cap binding	alg-1 (C. elegans) alg-2 (C. elegans) AGO1 (D. melanogaster)