POLR2E - KDM6A

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLR2E	ENSG00000099817	No diseases in record	No drugs in record	DNA binding DNA-directed 5'-3' RNA polymerase activity protein binding RNA polymerase I activity RNA polymerase II activity RNA polymerase III activity	RPB5 (S. cerevisiae) rpb-5 (C. elegans) Rpb5 (D. melanogaster)
KDM6A	ENSG00000147050	renal cell carcinoma bladder carcinoma oesophageal SCC MM medulloblastoma T-ALL other tumour types	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding chromatin DNA binding histone demethylase activity identical protein binding metal ion binding dioxygenase activity histone demethylase activity (H3-K27 specific)	CYC8 (S. cerevisiae) Utx (D. melanogaster)