POLR2E - ERCC3

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLR2E	ENSG00000099817	No diseases in record	No drugs in record	DNA binding DNA-directed 5'-3' RNA polymerase activity protein binding RNA polymerase I activity RNA polymerase II activity RNA polymerase III activity	RPB5 (S. cerevisiae) rpb-5 (C. elegans) Rpb5 (D. melanogaster)
ERCC3	ENSG00000163161	skin basal cell skin squamous cell melanoma	No drugs in record	DNA binding damaged DNA binding ATP-dependent DNA helicase activity helicase activity protein binding ATP binding GTP binding protein C-terminus binding transcription factor binding ATPase activity dATP binding peptide binding 3'-5' DNA helicase activity protein N-terminus binding protein kinase activity DNA-dependent ATPase activity RNA polymerase II carboxy-terminal domain kinase activity	SSL2 (S. cerevisiae) xpb-1 (C. elegans) hay (D. melanogaster)