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POLE - NPM1
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
POLE
ENSG00000177084
colorectal carcinoma
endometrioid carcinoma
stomach carcinoma
skin cancer
colorectal cancer susceptibility
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
nucleotide binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
zinc ion binding
single-stranded DNA 3'-5' exodeoxyribonuclease activity
4 iron, 4 sulfur cluster binding
POL2 (S. cerevisiae)
pole-1 (C. elegans)
DNApol-epsilon255 (D. melanogaster)
NPM1
ENSG00000181163
NHL
APL
AML
No drugs in record
transcription coactivator activity
RNA binding
protein kinase inhibitor activity
protein binding
protein kinase binding
Tat protein binding
histone binding
protein homodimerization activity
ribosomal large subunit binding
ribosomal small subunit binding
protein heterodimerization activity
NF-kappaB binding
unfolded protein binding
No GO terms in record