CAD - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CAD	ENSG00000084774	No diseases in record	No drugs in record	aspartate carbamoyltransferase activity carbamoyl-phosphate synthase (ammonia) activity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity dihydroorotase activity protein kinase activity ATP binding zinc ion binding enzyme binding identical protein binding aspartate binding RNA polymerase II regulatory region sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding	CPA2 (S. cerevisiae) pyr-1 (C. elegans) R (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)