NCK2 - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NCK2	ENSG00000071051	No diseases in record	No drugs in record	SH3/SH2 adaptor activity ARF guanyl-nucleotide exchange factor activity protein binding cytoskeletal adaptor activity receptor signaling complex scaffold activity protein complex binding scaffold protein binding	nck-1 (C. elegans) dock (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)