ASH2L - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ASH2L	ENSG00000129691	No diseases in record	No drugs in record	DNA binding protein binding beta-catenin binding histone-lysine N-methyltransferase activity transcription regulatory region DNA binding metal ion binding euchromatin binding histone methyltransferase activity (H3-K4 specific)	ash-2 (C. elegans) ash2 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)