EPAS1 - SKI

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EPAS1	ENSG00000116016	paraganglioma pheochromocytoma central nervous system hemangioblastomas	No drugs in record	RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding protein binding transcription factor binding histone acetyltransferase binding protein heterodimerization activity sequence-specific DNA binding	hif-1 (C. elegans)
SKI	ENSG00000157933	melanoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding transcription corepressor activity protein binding zinc ion binding protein kinase binding protein domain specific binding ubiquitin protein ligase binding SMAD binding histone deacetylase inhibitor activity repressing transcription factor binding	Snoo (D. melanogaster)