RUNX2 - SKI

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RUNX2	ENSG00000124813	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding ATP binding protein domain specific binding bHLH transcription factor binding repressing transcription factor binding	rnt-1 (C. elegans) run (D. melanogaster) lz (D. melanogaster)
SKI	ENSG00000157933	melanoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding transcription corepressor activity protein binding zinc ion binding protein kinase binding protein domain specific binding ubiquitin protein ligase binding SMAD binding histone deacetylase inhibitor activity repressing transcription factor binding	Snoo (D. melanogaster)