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POLA1 - NRG1
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
POLA1
ENSG00000101868
No diseases in record
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
NELARABINE
nucleotide binding
nucleoside binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
protein binding
3'-5' exonuclease activity
protein kinase binding
metal ion binding
protein heterodimerization activity
4 iron, 4 sulfur cluster binding
DNA primase activity
POL1 (S. cerevisiae)
DNApol-alpha180 (D. melanogaster)
NRG1
ENSG00000157168
NSCLC
No drugs in record
transcription cofactor activity
protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
cytokine activity
ErbB-2 class receptor binding
integrin binding
growth factor activity
transmembrane receptor protein tyrosine kinase activator activity
receptor tyrosine kinase binding
ErbB-3 class receptor binding
chemorepellent activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription factor binding
DNA binding
sequence-specific DNA binding
metal ion binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II repressing transcription factor binding
nucleic acid binding
No GO terms in record