POLA1 - ERCC5

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
POLA1 ENSG00000101868

No diseases in record

CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
NELARABINE
nucleotide binding
nucleoside binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
protein binding
3'-5' exonuclease activity
protein kinase binding
metal ion binding
protein heterodimerization activity
4 iron, 4 sulfur cluster binding
DNA primase activity
POL1 (S. cerevisiae)
DNApol-alpha180 (D. melanogaster)
ERCC5 ENSG00000134899 skin basal cell
skin squamous cell
melanoma

No drugs in record

bubble DNA binding
double-stranded DNA binding
single-stranded DNA binding
endodeoxyribonuclease activity
protein binding
protein homodimerization activity
metal ion binding
protein N-terminus binding
RAD2 (S. cerevisiae)
xpg-1 (C. elegans)