TNK2 - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TNK2	ENSG00000061938	No diseases in record	No drugs in record	protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity GTPase inhibitor activity epidermal growth factor receptor binding protein binding ATP binding ubiquitin protein ligase binding identical protein binding metal ion binding WW domain binding	Ack (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)