PHF8 - PRMT5

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PHF8	ENSG00000172943	No diseases in record	No drugs in record	chromatin binding iron ion binding protein binding zinc ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors histone demethylase activity histone demethylase activity (H3-K9 specific) methylated histone binding histone demethylase activity (H4-K20 specific) histone demethylase activity (H3-K36 specific) histone demethylase activity (H3-K27 specific)	JHD1 (S. cerevisiae)
PRMT5	ENSG00000100462	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding transcription corepressor activity protein binding methyltransferase activity methyl-CpG binding histone-arginine N-methyltransferase activity protein-arginine N-methyltransferase activity protein complex binding protein-arginine omega-N symmetric methyltransferase activity ribonucleoprotein complex binding histone methyltransferase activity (H4-R3 specific) protein heterodimerization activity	HSL7 (S. cerevisiae) prmt-5 (C. elegans) csul (D. melanogaster)