POLA1 - ETV6

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
POLA1 ENSG00000101868

No diseases in record

CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
NELARABINE
nucleotide binding
nucleoside binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
protein binding
3'-5' exonuclease activity
protein kinase binding
metal ion binding
protein heterodimerization activity
4 iron, 4 sulfur cluster binding
DNA primase activity
POL1 (S. cerevisiae)
DNApol-alpha180 (D. melanogaster)
ETV6 ENSG00000139083 congenital fibrosarcoma
multiple different leukaemia and lymphoma tumour types including ALL
secretory breast
MDS

No drugs in record

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein domain specific binding
aop (D. melanogaster)