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POLE - RUVBL2
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
POLE
ENSG00000177084
colorectal carcinoma
endometrioid carcinoma
stomach carcinoma
skin cancer
colorectal cancer susceptibility
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
nucleotide binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
zinc ion binding
single-stranded DNA 3'-5' exodeoxyribonuclease activity
4 iron, 4 sulfur cluster binding
POL2 (S. cerevisiae)
pole-1 (C. elegans)
DNApol-epsilon255 (D. melanogaster)
RUVBL2
ENSG00000183207
No diseases in record
No drugs in record
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
DNA helicase activity
ATP-dependent DNA helicase activity
protein binding
ATP binding
chromatin DNA binding
identical protein binding
ATP-dependent 5'-3' DNA helicase activity
unfolded protein binding
ATPase activity
RVB2 (S. cerevisiae)
rept (D. melanogaster)