KDM1A - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KDM1A	ENSG00000004487	No diseases in record	No drugs in record	RNA polymerase II transcription factor binding p53 binding chromatin binding transcription factor activity, sequence-specific DNA binding histone deacetylase activity protein binding transcription factor binding oxidoreductase activity enzyme binding ligand-dependent nuclear receptor transcription coactivator activity demethylase activity histone demethylase activity histone demethylase activity (H3-K4 specific) histone demethylase activity (H3-K9 specific) histone demethylase activity (H3-dimethyl-K4 specific) telomeric DNA binding MRF binding transcription regulatory region DNA binding flavin adenine dinucleotide binding androgen receptor binding telomeric repeat-containing RNA binding	Su(var)3-3 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)