POLA1 - IDH1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLA1	ENSG00000101868	No diseases in record	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE NELARABINE	nucleotide binding nucleoside binding DNA binding chromatin binding DNA-directed DNA polymerase activity protein binding 3'-5' exonuclease activity protein kinase binding metal ion binding protein heterodimerization activity 4 iron, 4 sulfur cluster binding DNA primase activity	POL1 (S. cerevisiae) DNApol-alpha180 (D. melanogaster)
IDH1	ENSG00000138413	glioblastoma	No drugs in record	magnesium ion binding isocitrate dehydrogenase (NADP+) activity receptor binding protein homodimerization activity NADP binding NAD binding (R)-2-hydroxyglutarate dehydrogenase activity cadherin binding involved in cell-cell adhesion isocitrate dehydrogenase (NAD+) activity catalytic activity oxidoreductase activity RNA binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor metal ion binding	IDP1 (S. cerevisiae) IDP2 (S. cerevisiae) IDP3 (S. cerevisiae)