AXIN1 - POLE

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
AXIN1 ENSG00000103126 colorectal
endometrial
prostate
hepatocellular carcinoma
hepatoblastoma
sporadic medulloblastoma

No drugs in record

signal transducer activity
GTPase activator activity
protein binding
beta-catenin binding
enzyme binding
protein kinase binding
receptor signaling complex scaffold activity
ubiquitin protein ligase binding
protein complex scaffold activity
identical protein binding
protein homodimerization activity
SMAD binding
armadillo repeat domain binding
I-SMAD binding
Axn (D. melanogaster)
POLE ENSG00000177084 colorectal carcinoma
endometrioid carcinoma
stomach carcinoma
skin cancer
colorectal cancer susceptibility
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
nucleotide binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
zinc ion binding
single-stranded DNA 3'-5' exodeoxyribonuclease activity
4 iron, 4 sulfur cluster binding
POL2 (S. cerevisiae)
pole-1 (C. elegans)
DNApol-epsilon255 (D. melanogaster)