TCF3 - IRS1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TCF3	ENSG00000071564	pre B-ALL	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding mitogen-activated protein kinase kinase kinase binding enhancer binding protein homodimerization activity bHLH transcription factor binding protein heterodimerization activity repressing transcription factor binding vitamin D response element binding E-box binding	hlh-2 (C. elegans)
IRS1	ENSG00000169047	No diseases in record	No drugs in record	signal transducer activity transmembrane receptor protein tyrosine kinase adaptor activity protein kinase C binding Ras guanyl-nucleotide exchange factor activity insulin receptor binding insulin-like growth factor receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH2 domain binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity tRNA binding aminoacyl-tRNA editing activity ATP binding isoleucine-tRNA ligase activity	chico (D. melanogaster)