CBLB - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CBLB	ENSG00000114423	AML	No drugs in record	phosphotyrosine residue binding ubiquitin-protein transferase activity signal transducer activity calcium ion binding protein binding zinc ion binding ligase activity SH3 domain binding receptor tyrosine kinase binding ubiquitin protein ligase activity	sli-1 (C. elegans) Cbl (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)