SMAD7 - MED12

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMAD7	ENSG00000101665	No diseases in record	No drugs in record	transcription factor activity, sequence-specific DNA binding protein binding collagen binding beta-catenin binding transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity ubiquitin protein ligase binding type I transforming growth factor beta receptor binding transcription regulatory region DNA binding metal ion binding activin binding I-SMAD binding	daf-14 (C. elegans) daf-8 (C. elegans) Dad (D. melanogaster)
MED12	ENSG00000184634	uterine leiomyoma fibroadenoma phyllodes tumour	No drugs in record	RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription cofactor activity RNA polymerase II transcription coactivator activity chromatin binding transcription cofactor activity transcription coactivator activity receptor activity protein binding beta-catenin binding protein C-terminus binding protein domain specific binding ligand-dependent nuclear receptor transcription coactivator activity vitamin D receptor binding thyroid hormone receptor binding ubiquitin protein ligase activity	dpy-22 (C. elegans) kto (D. melanogaster)