LIG4 - ERBB4

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
LIG4	ENSG00000174405	No diseases in record	No drugs in record	DNA binding DNA ligase activity DNA ligase (ATP) activity protein binding ATP binding protein C-terminus binding ligase activity metal ion binding	DNL4 (S. cerevisiae) lig-4 (C. elegans) Lig4 (D. melanogaster)
ERBB4	ENSG00000178568	melanoma gastric NSCLC	AFATINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding protein binding ATP binding protein homodimerization activity transcription regulatory region DNA binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	let-23 (C. elegans) Egfr (D. melanogaster)