MTA2 - POLE

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
MTA2 ENSG00000149480

No diseases in record

No drugs in record

transcription factor activity, transcription factor binding
RNA polymerase II transcription factor binding
RNA polymerase II repressing transcription factor binding
transcription factor activity, sequence-specific DNA binding
histone deacetylase activity
protein binding
zinc ion binding
histone deacetylase binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
nucleosomal DNA binding
lin-40 (C. elegans)
MTA1-like (D. melanogaster)
POLE ENSG00000177084 colorectal carcinoma
endometrioid carcinoma
stomach carcinoma
skin cancer
colorectal cancer susceptibility
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
nucleotide binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
zinc ion binding
single-stranded DNA 3'-5' exodeoxyribonuclease activity
4 iron, 4 sulfur cluster binding
POL2 (S. cerevisiae)
pole-1 (C. elegans)
DNApol-epsilon255 (D. melanogaster)