POLA1 - EXO1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLA1	ENSG00000101868	No diseases in record	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE NELARABINE	nucleotide binding nucleoside binding DNA binding chromatin binding DNA-directed DNA polymerase activity protein binding 3'-5' exonuclease activity protein kinase binding metal ion binding protein heterodimerization activity 4 iron, 4 sulfur cluster binding DNA primase activity	POL1 (S. cerevisiae) DNApol-alpha180 (D. melanogaster)
EXO1	ENSG00000174371	No diseases in record	No drugs in record	DNA binding chromatin binding RNA-DNA hybrid ribonuclease activity exonuclease activity protein binding 5'-3' exonuclease activity 5'-3' exodeoxyribonuclease activity single-stranded DNA 5'-3' exodeoxyribonuclease activity metal ion binding flap endonuclease activity double-stranded DNA 5'-3' exodeoxyribonuclease activity 5'-flap endonuclease activity hydrolase activity catalytic activity nuclease activity hydrolase activity, acting on ester bonds double-stranded DNA binding	DIN7 (S. cerevisiae) EXO1 (S. cerevisiae) exo-1 (C. elegans) tos (D. melanogaster)