CBL - ERCC3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CBL	ENSG00000110395	AML JMML MDS	No drugs in record	phosphotyrosine residue binding transcription factor activity, sequence-specific DNA binding ubiquitin-protein transferase activity signal transducer activity calcium ion binding protein binding zinc ion binding ligase activity SH3 domain binding receptor tyrosine kinase binding phosphatidylinositol 3-kinase regulatory subunit binding ephrin receptor binding ubiquitin protein ligase activity cadherin binding involved in cell-cell adhesion	sli-1 (C. elegans) Cbl (D. melanogaster)
ERCC3	ENSG00000163161	skin basal cell skin squamous cell melanoma	No drugs in record	DNA binding damaged DNA binding ATP-dependent DNA helicase activity helicase activity protein binding ATP binding GTP binding protein C-terminus binding transcription factor binding ATPase activity dATP binding peptide binding 3'-5' DNA helicase activity protein N-terminus binding protein kinase activity DNA-dependent ATPase activity RNA polymerase II carboxy-terminal domain kinase activity	SSL2 (S. cerevisiae) xpb-1 (C. elegans) hay (D. melanogaster)