CBL - PTCH1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CBL	ENSG00000110395	AML JMML MDS	No drugs in record	phosphotyrosine residue binding transcription factor activity, sequence-specific DNA binding ubiquitin-protein transferase activity signal transducer activity calcium ion binding protein binding zinc ion binding ligase activity SH3 domain binding receptor tyrosine kinase binding phosphatidylinositol 3-kinase regulatory subunit binding ephrin receptor binding ubiquitin protein ligase activity cadherin binding involved in cell-cell adhesion	sli-1 (C. elegans) Cbl (D. melanogaster)
PTCH1	ENSG00000185920	skin basal cell medulloblastoma	No drugs in record	patched binding smoothened binding protein binding hedgehog receptor activity heparin binding cholesterol binding cyclin binding protein complex binding hedgehog family protein binding	NCR1 (S. cerevisiae) ptc-1 (C. elegans) ptc-3 (C. elegans) ptc-2 (C. elegans) ptc (D. melanogaster)