CCND1 - LEF1

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CCND1	ENSG00000110092	CLL B-ALL breast	PALBOCICLIB	transcription corepressor activity protein kinase activity protein binding transcription factor binding cyclin-dependent protein serine/threonine kinase regulator activity enzyme binding protein kinase binding protein complex binding histone deacetylase binding proline-rich region binding	cyd-1 (C. elegans) CycD (D. melanogaster)
LEF1	ENSG00000138795	B-ALL T-ALL eyelid sebaceous carcinoma AML lymphomas	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding beta-catenin binding transcription factor binding DNA binding, bending estrogen receptor activity estrogen receptor binding enhancer binding histone binding histone deacetylase binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process sequence-specific DNA binding transcription regulatory region DNA binding gamma-catenin binding armadillo repeat domain binding C2H2 zinc finger domain binding	pop-1 (C. elegans) pan (D. melanogaster)