POLA1 - CALR

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLA1	ENSG00000101868	No diseases in record	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE NELARABINE	nucleotide binding nucleoside binding DNA binding chromatin binding DNA-directed DNA polymerase activity protein binding 3'-5' exonuclease activity protein kinase binding metal ion binding protein heterodimerization activity 4 iron, 4 sulfur cluster binding DNA primase activity	POL1 (S. cerevisiae) DNApol-alpha180 (D. melanogaster)
CALR	ENSG00000179218	MPN MDS	No drugs in record	complement component C1q binding glycoprotein binding DNA binding mRNA binding integrin binding iron ion binding calcium ion binding protein binding zinc ion binding carbohydrate binding ubiquitin protein ligase binding peptide binding hormone binding protein binding involved in protein folding androgen receptor binding unfolded protein binding chaperone binding	CNE1 (S. cerevisiae) crt-1 (C. elegans)