POLA1 - RUNX1

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
POLA1 ENSG00000101868

No diseases in record

CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
NELARABINE
nucleotide binding
nucleoside binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
protein binding
3'-5' exonuclease activity
protein kinase binding
metal ion binding
protein heterodimerization activity
4 iron, 4 sulfur cluster binding
DNA primase activity
POL1 (S. cerevisiae)
DNApol-alpha180 (D. melanogaster)
RUNX1 ENSG00000159216 AML
pre B-ALL
T-ALL

No drugs in record

regulatory region DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
ATP binding
rnt-1 (C. elegans)
run (D. melanogaster)
lz (D. melanogaster)