PMS2 - MED12

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PMS2	ENSG00000122512	colorectal endometrial ovarian medulloblastoma glioma	No drugs in record	DNA binding endonuclease activity protein binding ATP binding ATPase activity single base insertion or deletion binding single-stranded DNA binding MutSalpha complex binding mismatched DNA binding	PMS1 (S. cerevisiae) Pms2 (D. melanogaster)
MED12	ENSG00000184634	uterine leiomyoma fibroadenoma phyllodes tumour	No drugs in record	RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription cofactor activity RNA polymerase II transcription coactivator activity chromatin binding transcription cofactor activity transcription coactivator activity receptor activity protein binding beta-catenin binding protein C-terminus binding protein domain specific binding ligand-dependent nuclear receptor transcription coactivator activity vitamin D receptor binding thyroid hormone receptor binding ubiquitin protein ligase activity	dpy-22 (C. elegans) kto (D. melanogaster)