PIAS2 - AGO2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PIAS2	ENSG00000078043	No diseases in record	No drugs in record	DNA binding transcription coactivator activity protein binding transcription factor binding zinc ion binding ligase activity SUMO transferase activity ubiquitin protein ligase binding androgen receptor binding SUMO ligase activity	NFI1 (S. cerevisiae) SIZ1 (S. cerevisiae) gei-17 (C. elegans) Su(var)2-10 (D. melanogaster)
AGO2	ENSG00000123908	No diseases in record	No drugs in record	RNA 7-methylguanosine cap binding RNA polymerase II core binding core promoter binding double-stranded RNA binding single-stranded RNA binding mRNA binding translation initiation factor activity endoribonuclease activity protein binding protein C-terminus binding bidentate ribonuclease III activity siRNA binding miRNA binding metal ion binding endoribonuclease activity, cleaving siRNA-paired mRNA endoribonuclease activity, cleaving miRNA-paired mRNA mRNA cap binding	alg-1 (C. elegans) alg-2 (C. elegans) AGO1 (D. melanogaster)