VPS4B - SMAD3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
VPS4B	ENSG00000119541	No diseases in record	No drugs in record	protein binding ATP binding protein C-terminus binding ATPase activity ATPase activity, coupled identical protein binding protein homodimerization activity microtubule-severing ATPase activity	VPS4 (S. cerevisiae) vps-4 (C. elegans)
SMAD3	ENSG00000166949	colorectal carcinoma oral squamous cell carcinoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter sequence-specific core promoter proximal region sequence-specific DNA binding RNA polymerase II activating transcription factor binding transcription factor activity, sequence-specific DNA binding transforming growth factor beta receptor binding protein binding collagen binding beta-catenin binding transcription factor binding zinc ion binding protein kinase binding phosphatase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity chromatin DNA binding ubiquitin protein ligase binding enhancer binding identical protein binding protein homodimerization activity ubiquitin binding bHLH transcription factor binding sequence-specific DNA binding transcription regulatory region DNA binding protein heterodimerization activity co-SMAD binding R-SMAD binding transcription factor activity, protein binding	sma-3 (C. elegans) sma-2 (C. elegans)