RUNX2 - BCR

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RUNX2	ENSG00000124813	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding ATP binding protein domain specific binding bHLH transcription factor binding repressing transcription factor binding	rnt-1 (C. elegans) run (D. melanogaster) lz (D. melanogaster)
BCR	ENSG00000186716	CML ALL AML	PONATINIB	protein serine/threonine kinase activity protein tyrosine kinase activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding ATP binding kinase activity enzyme binding	BEM2 (S. cerevisiae)