DIS3 - FOXO3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DIS3	ENSG00000083520	No diseases in record	No drugs in record	3'-5'-exoribonuclease activity RNA binding endonuclease activity guanyl-nucleotide exchange factor activity protein binding tRNA binding endoribonuclease activity nuclease activity exonuclease activity hydrolase activity nucleic acid binding exoribonuclease activity Ran GTPase binding ribonuclease activity	DIS3 (S. cerevisiae) dis-3 (C. elegans) Dis3 (D. melanogaster)
FOXO3	ENSG00000118689	AL	No drugs in record	core promoter binding transcription cofactor binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding beta-catenin binding protein kinase binding chromatin DNA binding sequence-specific DNA binding	HCM1 (S. cerevisiae) daf-16 (C. elegans) foxo (D. melanogaster)