STK11 - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
STK11	ENSG00000118046	NSCLC pancreatic jejunal hamartoma ovarian testicular	No drugs in record	magnesium ion binding p53 binding protein serine/threonine kinase activity protein binding ATP binding LRR domain binding protein kinase activator activity	SAK1 (S. cerevisiae) TOS3 (S. cerevisiae) par-4 (C. elegans) lkb1 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)