POLE - USP7

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)
USP7	ENSG00000187555	No diseases in record	No drugs in record	p53 binding cysteine-type endopeptidase activity thiol-dependent ubiquitin-specific protease activity protein binding protein C-terminus binding transcription factor binding ubiquitin protein ligase binding	UBP15 (S. cerevisiae) Usp7 (D. melanogaster)