HIF1A - HIP1

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HIF1A	ENSG00000100644	endometrioid carcinoma glioblastoma colorectal renal lung pancreatic	No drugs in record	transcription factor activity, transcription factor binding transcription factor activity, RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding transcription factor binding enzyme binding protein kinase binding ubiquitin protein ligase binding histone acetyltransferase binding nuclear hormone receptor binding histone deacetylase binding protein heterodimerization activity Hsp90 protein binding sequence-specific DNA binding	hif-1 (C. elegans)
HIP1	ENSG00000127946	CMML NSCLC	No drugs in record	epidermal growth factor receptor binding structural constituent of cytoskeleton protein binding clathrin binding clathrin light chain binding phosphatidylinositol-3-phosphate binding phosphatidylinositol binding glutamate receptor binding AP-2 adaptor complex binding clathrin adaptor activity protein homodimerization activity phosphatidylinositol-3,4-bisphosphate binding protein heterodimerization activity actin filament binding phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-4,5-bisphosphate binding high-affinity L-histidine transmembrane transporter activity antiporter activity actin binding phospholipid binding transcription corepressor activity	SLA2 (S. cerevisiae) Hip1 (D. melanogaster)