MLH1 - E2F1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MLH1	ENSG00000076242	colorectal endometrial ovarian CNS tumours CNS	No drugs in record	chromatin binding protein binding ATP binding ATPase activity guanine/thymine mispair binding single-stranded DNA binding MutSalpha complex binding mismatched DNA binding heteroduplex DNA loop binding DNA insertion or deletion binding dinucleotide insertion or deletion binding double-stranded DNA binding DNA binding	MLH1 (S. cerevisiae) Mlh1 (D. melanogaster)
E2F1	ENSG00000101412	No diseases in record	No drugs in record	core promoter binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding protein kinase binding sequence-specific DNA binding protein dimerization activity RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II regulatory region DNA binding	E2f1 (D. melanogaster)