TOP2B - GLI1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
GLI1	ENSG00000111087	CRC oesophagus cancer	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding DNA binding chromatin binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding microtubule binding transcription regulatory region DNA binding metal ion binding	tra-1 (C. elegans)