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Slorth
TOP2B - SKI
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
TOP2B
ENSG00000077097
No diseases in record
ETOPOSIDE
TENIPOSIDE
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA binding, bending
enzyme binding
histone deacetylase binding
metal ion binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)
SKI
ENSG00000157933
melanoma
No drugs in record
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription corepressor activity
protein binding
zinc ion binding
protein kinase binding
protein domain specific binding
ubiquitin protein ligase binding
SMAD binding
histone deacetylase inhibitor activity
repressing transcription factor binding
Snoo (D. melanogaster)