TOP2B - PLCG1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
PLCG1	ENSG00000124181	angiosarcoma	No drugs in record	phosphatidylinositol phospholipase C activity phospholipase C activity signal transducer activity, downstream of receptor neurotrophin TRKA receptor binding calcium ion binding protein binding protein kinase binding receptor tyrosine kinase binding glutamate receptor binding	PLC1 (S. cerevisiae) plc-3 (C. elegans) sl (D. melanogaster)