SMARCB1 - KDM5B

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMARCB1	ENSG00000099956	malignant rhabdoid	No drugs in record	RNA polymerase I CORE element sequence-specific DNA binding p53 binding DNA binding transcription coactivator activity protein binding Tat protein binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	SFH1 (S. cerevisiae) snfc-5 (C. elegans) Snr1 (D. melanogaster)
KDM5B	ENSG00000117139	No diseases in record	No drugs in record	DNA binding transcription factor activity, sequence-specific DNA binding transcription corepressor activity protein binding zinc ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors histone demethylase activity histone demethylase activity (H3-K4 specific) histone demethylase activity (H3-trimethyl-K4 specific) histone demethylase activity (H3-dimethyl-K4 specific)	JHD2 (S. cerevisiae) rbr-2 (C. elegans) Jarid2 (D. melanogaster)